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Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets

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Original price was: $37.84.Current price is: $22.98.


Price: $37.84 - $22.98
(as of Jun 29, 2025 15:58:52 UTC – Details)


With one Prilosec OTC pill each morning, block your heartburn for a full 24 hours.* Heartburn happens when stomach acid refluxes into the esophagus. Prilosec OTC’s delayed-release formula helps it pass through the tough stomach acid, preventing excess acid production to block frequent heartburn.* Some other heartburn relief treatments only neutralize the stomach acid after it’s already been produced and provide shorter relief (less than 24 hours). Prilosec OTC is the #1 Doctor and Gastroenterologist recommended frequent heartburn medicine for over 15 years.† Prilosec OTC’s active ingredient, 20 mg of delayed released omeprazole, works to fight heartburn differently from treatments like acid controllers/H2s or antacids. Omeprazole blocks heartburn for a full 24 hours after taking one pill each morning.* Omeprazole is a proton pump inhibitor (PPI) and PPIs are a powerful class of frequent heartburn medicines. PPIs block heartburn by preventing excess acid production…something that antacids just can’t do. With 1 Prilosec OTC pill each morning, block heartburn for 24 hours,* unlike antacids which last only 1-3 hours. * Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Compared to how antacids for heartburn. Use all heartburn medications as directed. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Not for immediate relief. † IQVIA ProVoice Survey, 2005 – 2022. ^ Check with insurance provider
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 2.32 x 4.75 x 3.7 inches; 2.47 ounces
Item model number ‏ : ‎ OTC
Date First Available ‏ : ‎ December 1, 2003
Manufacturer ‏ : ‎ Procter & Gamble
ASIN ‏ : ‎ B0000AN9L7
TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week
With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours
PREVENT EXCESS ACID PRODUCTION for heartburn relief that lasts for 24 HOURS.* Starts working on DAY 1*
CONTAINS ACTIVE INGREDIENT OMEPRAZOLE delayed-release 20mg, an acid reducer that provides long-lasting, heartburn relief*
#1 DOCTOR and GASTROENTEROLOGIST RECOMMENDED frequent heartburn medicine for over 15 years. FSA and HSA eligible

Customers say

Customers find this medication effective, noting it works better than prescribed antacids and starts working immediately. The product provides heartburn relief and stops acid reflux, lasting all day with one tablet every three days. Customers appreciate its excellent price, convenience, and ease of swallowing, with one customer mentioning it’s easy to take along. While some customers report no discernible taste, others mention a nasty taste.

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